CD81

CD81
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 1G8Q, 1IV5, 3X0E, 5DFW, 5DFV
Identifikatori
Aliasi	CD81
Vanjski ID-jevi	OMIM: 186845 MGI: 1096398 HomoloGene: 20915 GeneCards: CD81
Lokacija gena (čovjek) Hrom. Hromosom 11 (čovjek)[1] Bend 11p15.5 Početak 2,376,177 bp[1] Kraj 2,397,397 bp[1]
Lokacija gena (miš) Hrom. Hromosom 7 (miš)[2] Bend 7 F5|7 88.1 cM Početak 142,606,476 bp[2] Kraj 142,621,671 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine • MHC class II protein complex binding • transferrin receptor binding • virus receptor activity • integrin binding • cholesterol binding • lipid binding Ćelijska komponenta • integral component of membrane • Vezikula • membrana • focal adhesion • integral component of plasma membrane • immunological synapse • Egzosom • ćelijska membrana • basolateral plasma membrane Biološki proces • positive regulation of 1-phosphatidylinositol 4-kinase activity • GO:0034613 protein localization • regulation of protein stability • receptor internalization • cellular response to low-density lipoprotein particle stimulus • regulation of cell motility • receptor-mediated virion attachment to host cell • protein localization to lysosome • cell surface receptor signaling pathway • positive regulation of B cell proliferation • positive regulation of cell population proliferation • regulation of immune response • positive regulation of peptidyl-tyrosine phosphorylation • viral entry into host cell • positive regulation of protein catabolic process in the vacuole • Ćelijska proliferacija • GO:0022415 viral process • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • regulation of complement activation • humoral immune response mediated by circulating immunoglobulin • protein localization to plasma membrane • adaptive immune response • immune system process Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	975	12520
Ensembl	ENSG00000110651	ENSMUSG00000037706
UniProt	P60033	P35762
RefSeq (mRNK)	NM_001297649 NM_004356	NM_133655
RefSeq (bjelančevina)	NP_001284578 NP_004347	NP_598416
Lokacija (UCSC)	Chr 11: 2.38 – 2.4 Mb	Chr 7: 142.61 – 142.62 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Molekula CD81, znana i kao CD81 (eng. skr. Cluster of Differentiation 81), je protein koji je kod ljudi kodiran genom CD81.^[5][6] Također je poznata i kao površinskoćelijski 26 kDa-ski protein TAPA-1 (Target of the Antiproliferative Antibody 1) i tetraspanin-28 (Tspan-28).

1. ^ ^{a b c} GRCh38: Ensembl release 89: ENSG00000110651 - Ensembl, maj 2017
2. ^ ^{a b c} GRCm38: Ensembl release 89: ENSMUSG00000037706 - Ensembl, maj 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: CD81 CD81 molecule".
6. ^ Andria ML, Hsieh CL, Oren R, Francke U, Levy S (august 1991). "Genomic organization and chromosomal localization of the TAPA-1 gene". Journal of Immunology. 147 (3): 1030–6. PMID 1650385.